Splice

Delphine Chanéac stars as Dren, a living science project, in the film Splice.

And if her feet look a little weird, that's because Dren is not completely human.

She's tied down to a table by Elsa, a scientist played by Sarah Polley, who's going to perform surgery on her.

This is obviously one of the more stranger BF bondage scenes--but the bound woman IS barefoot.

Splice is a very good movie, overall. It's a great, modern day science fiction retelling of the Frankenstein tale. Its director, Vincenzo Natali, also helmed the first Cube.